Inflammatory Reactions of Rosacea: Understanding What Happens to Your Skin

 Main Inflammatory Reactions in Rosacea

1. Overactive Immune System

The skin’s defense system overreacts, producing inflammatory substances that increase redness and sensitivity.

🔹 The skin produces too much cathelicidin (LL-37) → this leads to inflammation and dilated blood vessels.

🔹 Immune cells, such as neutrophils and mast cells, become overactive, worsening irritation.

 2. Sensitivity to External Triggers (Neurogenic Inflammation)

 The skin’s nervous system is more sensitive, so any environmental change can cause an exaggerated reaction.

🔹 Mast cells release histamine (a substance involved in allergies) → this increases burning sensations and redness. 

🔹 Stress and temperature changes (hot/cold) activate skin nerves, intensifying inflammation.

 3. Dilated and Persistent Blood Vessels

Rosacea alters the facial blood vessels, making them more visible and prone to chronic redness. 

🔹 The skin develops new blood vessels (angiogenesis), making redness more persistent. 🔹 The body produces VEGF (Vascular Endothelial Growth Factor), which keeps blood vessels dilated for longer.

4. Imbalance in the Skin Microbiome

 Healthy skin has a balanced ecosystem of microorganisms, but in rosacea, this balance is disrupted.

🔹 The Demodex folliculorum mite (naturally present on the skin) multiplies excessively, triggering inflammation.

🔹 The skin microbiome changes, making it more vulnerable to irritation and inflammation.

 5. Damage from Free Radicals and Environmental Factors

Exposure to sunlight, pollution, and other environmental stressors increases oxidative stress, making the skin even more sensitive. 

🔹 UV radiation and pollution increase free radical production, damaging skin cells.

🔹 A weakened skin barrier leaves the skin more exposed to inflammation and irritation.

 How to Care for Rosacea-Prone Skin?

 There is no cure for rosacea, but with the right care, symptoms can be managed. Some key strategies include:

 ✔ Using products with soothing and antioxidant ingredients to reduce inflammation.

✔ Strengthening the skin barrier with moisturizers that restore balance.

 ✔ Protecting the skin from pollution and sun exposure to prevent flare-ups.

At Seoul kissed, we believe in a skincare approach that respects sensitive skin, combining Korean innovation with the powerful benefits of Amazonian ingredients to restore balance and strengthen the skin. It’s not just about treating symptoms but creating a daily ritual that protects and brings comfort.

If you live with rosacea, remember: your skin needs patience, care, and formulas that work in harmony with its nature. You’re not alone on this journey